Nootropics, or better known as ‘smart drugs,’ are swiftly gaining attention across the globe for their rapid and effective outcomes. They are attaining popularity among youngsters as well as adults for their benefits in the areas of attention improvement, memory enhancement, and increased cognitive performance.
Sunifiram is a new addition to the group of nootropics. Having similar effects like the racetam family drugs, positively impacts on the cognitive functions. With memory, learning and mood enhancing benefits, this particular drug delivers a much more powerful effect on the user as compared to other racetams.
Also known as DM-235, Sunifiram can serve as a strong supplement for mood and energy enhancement. Discovered only recently, this drug has very limited research available. However, the user experience, over the years, has proved that it is effective in boosting learning and memory.
Medical professionals are beginning to consider Sunifiram as a potential treatment for neurological disorders like Alzheimer’s and Parkinson’s disease. So far, there are no significant side effects reported for Sunifiram. There are still clinical trials going on to explore more about this cognitive enhancer. The research evidence so far has demonstrated promising results.
Sunifiram is an AMPA agonist and falls in the family of AMPAkine. According to scientific research, it is 1000 times more potent than Piracetam. So, if you are looking to improve your cognitive functioning and enhance your decision-making, Sunifiram is a completely safe and effective drug that helps you achieve more competence.
Sunifiram, though, emits similar effects like that of racetam drugs; it does not belong to this particular drug family. It is essentially a synthetic derivation of Piracetam, a strong cognitive enhancing drug. The chemical structure gets modified during the synthesis and this makes Sunifiram different than other racetam drugs.
Sunifiram operates in the hippocampus. It entails anti-amnesiac properties which makes it a cognitive booster. It gains its effectiveness through enhancing the glycine receptor binding. This makes it an AMPAkine. This nootropic drug works differently in all users, depending on their needs, conditions, and lifestyle.
Alzheimer’s patients, using Sunifiram, show positive progress. It tends to reverse the deficiency caused in their cognitive system. There is not much data available which describes the functioning mechanism of Sunifiram. However, professionals refer its functions to that of AMPAkine in the brain. Sunifiram enhances the glutamate levels in the brain, resulting in enhancing the ability to form and store memory.
- It promotes mental energy and focus in individuals
- Activates the AMPA receptors that are present in the brain.
- It increases the growth of synapses between the neurons.
4 Miracle Benefits For Sunifiram
Sunifiram is one of the recently discovered nootropic drugs that have the ability to improve your mental performance. It can increase your memory formation, enhance recall, and bring a positive change in your decision-making and mental processing abilities. This is the reason why it is rapidly gaining attention across the world.
Considering the fact that Sunifiram is 1000 times more potent than Piracetam, it is obvious that the user achieves more enhanced benefits from this drug than any other brain performance boosting racetam drugs. Here is a list of benefits that you can acquire through Sunifiram:
1.Improves Your Memory
Researchers have widely explored the impact of Sunifiram on the working memory of humans. According to the clinical trials, users report increased information recalling after the consumption of Sunifiram.
A couple of studies showcase that Sunifiram serves in improving long-term memory as well as the brain starts to form new connection regarding the memory retention. If you are a student or belong to a professional field which requires storage of extensive information, Sunifiram is the drug that can help you raise your performance bar.
2. Makes You Feel Motivated
Sunifiram operates directly in the brain. Though there is not adequate information to determine the exact mechanism of action for Sunifiram, its association with the glutamate level in the brain, presumably, increases the energy level in the user.
You will feel more energized and motivated after taking this performance-boosting drug. This is one reason why Sunifiram is popular among students and employees. Their enthusiasm level gets more boosted and they are able to perform their designated tasks with greater energy and more focus.
3. Helps You With Concentration
With the distractions available all around, it is very easy to lose focus and concentration during a task. If you are a student, you can relate how your mind gets diverted towards social media and other distractions around you whenever you try to study.
Similarly, for office workers, it is easier to delay the work until the very end. This is because your mind is unable to focus. Sunifiram can increase the levels of concentration and make you feel less distracted by the external elements. It can help you focus more on the provided tasks and limit the ability of your mind to lose concentration due to distractions.
4. Treats Anxiety And Depression
Though there is still a lot about this nootropic drug which requires research in this particular area, the studies so far do not project Sunifiram as an anti-depressant. However, it can substantially improve your mood and enhance your energy. This can result in helping you step out of your depressive mood and alleviate stress.
Despite the research gap, Sunifiram’s usage results are showing positive outcomes, proving it as an effective and safe drug to use. As a matter of fact, Sunifiram is much stronger than Piracetam. This means that the user can get more benefits in a smaller dose.
According to the users’ review and the data gathered through trials and research, the average dosage considered effective is 5 to 10 mg taken three times a day. Sublingual form of Sunifiram is best for maximum absorption.
To ensure maximum positive results, you should start taking Sunifiram with the smallest possible dose. You can gradually increase the dose as you get used to the effects and your body starts to accept the consumption. Though there are no adverse side effects, you may face fogging in the brain if you start with high doses right away.
You can stack Sunifiram with other nootropics but it is important for you to remain careful in such an attempt. It is better to get your physician’s opinion on dosage when you are planning to combine it with other supplements.
The scientific studies show Sunifiram has the ability to increase the signaling capability of NMDA receptor through enhancing the levels of PKCa phosphorylation. Sunifiram is dependent on the glycine binding site when it enters the body and then acts in contrast to the glycine itself. Sunifiram renders most of its effects through the AMPA receptor which is one of the three main subsets of glutamate receptors. The AMPA function gets enhanced as Sunifiram is able to enhance the signaling in the hippocampus through the glycine binding sites.
The functioning of Sunifiram is highly dose-dependent. To achieve NMDA-dependent long-term potentiation, it is important to orally take 0.01 – 1 mg/kg Sunifiram for 7 to 12 days.
Sunifiram increases the levels of acetylcholine release in the human body, resulting in positive results pertinent to conditions like Alzheimer’s and dementia. The effectiveness of the drug can vary from person to person as its functioning depends on the individual needs, conditions and the lifestyle carried by the patients.
Sunifiram is able to create a level of excitement among the nootropic supplements. Hinting at a highly promising future, users consider it as a potent drug that offers them cognitive benefits. According to the user reviews, “Sunifiram delivers sufficient improvement in mood, energy levels, concentration and focus, memory formation, and cognitive performance“.
If you are looking for a drug that is low in dose yet effective in functions, Sunifiram suffices your requirements just fine. Users report it as a safe and non-toxic drug that is an excellent addition to the nootropic arsenal.
Since Sunifiram is a new drug, it is not as well-known as some of the other nootropics like Piracetam. With the growth in research, we expect the scope of Sunifiram to widen further.
According to the available research data and the users’ review, there are no side effects documented for Sunifiram. They may emerge as researchers perform more trials and studies. The possibility, however, remains marginal. The research so far states that Sunifiram is both, safe and well tolerated. No reports denote toxicity in the drug at any dosage level.
You may face adverse effects like brain fog if you start taking higher doses of Sunifiram in the beginning. It is important that you give your body some time to accept the drug and get used to it.
Some of the users report minimal side effects when using Sunifiram. These minor effects that you may experience during Sunifiram intake are:
- Increase in body temperature
- Increased level of perspiration
- Nasal stuffiness
- Enhanced sensitivity to audio and visual stimulus
- Sleeping disorder (such as insomnia)
These effects rarely occur, and even if they do, they subside as your body gets used to the drug.
Sunifiram is not a drug that you can find easily at the local vendors. Despite its increasing popularity, it is not sold widely in the markets. However, if you want to buy Sunifiram, the best way to do is to get it online. This is the people across the globe are getting their nootropic stacks with convenience.
All you have to do to get Sunifiram is to click on this link. You will get your supplements right in your mail and you will be able to start taking it on a routine basis. We offer Sunifiram along with a diverse range of other nootropic supplements. Get your set of supplements today to see the positive results of Sunifiram yourself.
Sunifiram has the ability to inhibit the effects of several drugs used for the condition of amnesia. It can also reverse the effects induced in your body by drugs like mecamylamine and clonidine. You can stack this nootropic drug and combine it with other supplements and drugs. Collaboratively, they can produce more beneficial and effective cognitive results.
Nootropics like Piracetam and oxiracetam can be effectively stacked with Sunifiram and you can achieve higher cognitive performance than using Sunifiram alone. The reviews achieved by users support the positive results of stacking Sunifiram with these drugs. Stacking with Noopept, however, has received diverse feedback, indicating contrast in the reviews given by the users. Some state that stacking Sunifiram with Noopept can enhance focus, motivation, and mood extensively, while some report the exact opposite. As for caffeine and Modafinil-like stimulants, users hint unpleasant experiences.
Sunifiram has received mixed reviews from the user base but the positive effects are highly acclaimed. The drug, however, is still undergoing clinical trials and research, so the exact benefits and side effects are not known. Conversely, the response received from worldwide users indicates a promising future for Sunifiram. Users report no serious side effects and showcase their satisfaction with the drug in terms of cognitive enhancement and improved memory formation.
Sunifiram is effective as a standalone drug, as well as when you stack it with certain other supplements. You have to be careful in choosing which supplement to stack it with as there are no established facts about the reactions that may occur. Using this drug, if you ever experience symptoms like a headache, nausea or dizziness persistently, we advise you to seek out medical help immediately. Although you do not require any prescription to purchase this nootropic drug, it is better to get your doctor’s opinion before you start taking Sunifiram on a regular basis.
- A novel cognitive enhancer, ZSET1446/ST101, promotes hippocampal neurogenesis and ameliorates depressive behavior in olfactory bulbectomized mice.
- DM235 (sunifiram): a novel nootropic with potential as a cognitive enhancer.
- CaM kinase II and protein kinase C activations mediate enhancement of long-term potentiation by nefiracetam in the rat hippocampal CA1 region.
- AMPA-receptor activation is involved in the antiamnesic effect of DM 232 (unifiram) and DM 235 (sunifiram).
- Novel nootropic drug sunifiram enhances hippocampal synaptic efficacy via glycine-binding site of N-methyl-D-aspartate receptor.
- 2-pyrrolidinone moiety is not critical for the cognition-enhancing activity of piracetam-like drugs.
- Molecular simplification of 1,4-diazabicyclo[4.3.0]nonan-9-ones gives piperazine derivatives that maintain high nootropic activity.
- Design, synthesis and preliminary pharmacological evaluation of new piperidine and piperazine derivatives as cognition-enhancers.
- Design, synthesis and nootropic activity of new analogues of sunifiram and sapunifiram, two potent cognition-enhancers.
- Novel nootropic drug sunifiram improves cognitive deficits via CaM kinase II and protein kinase C activation in olfactory bulbectomized mice.