Noopept is one of the most recent nootropics discovered in the field of medical science. This discovery happened in 1995 but it still remains grossly understudied.
Previously, the compound was only known for its beneficial effects for subduing symptoms of Alzheimer’s, dementia and other brain diseases that cause memory degeneration. Over the years, scientists have started to unravel other benefits of Noopept on the brain and its cognitive functions.
Since then the nootropic remains to be very popular in medical circles. Some even consider as the best nootropic available in the market.
This is for two reasons:
- The drug is highly effective in speeding up the cognitive functions (e.g. memory retention, focus, and alertness)
- Its dosage is very small in comparison to other nootropics
Due to this researchers have recently started taking an interest in the compound’s composition and mechanism. This is to determine if the compound is safe to use and how many benefits are still unknown.
What do we know about Noopept?
For starters, we know that the drug was patented in Russia. At that time medical practitioners used it to help reduce age symptoms of the brain like memory loss and short attention span.
Furthermore, the compound is a synthetic peptide scientifically known as N-phenylacetyl-L-prolylglycine ethyl ester. This means that it is a chain of amino acids connected to each other by peptide bonds. Many relate its chemical structure to that of piracetam (racetam family) even though it doesn’t have the pyrrolidone cycle.
This fact makes it unique and probably provides it higher solubility than other nootropics.
- Improve learning capacity, focus, and concentration.
- Improves the speed of recalling things.
- Lowers stress and anxiety.
After oral intake, Noopept trickles into the blood-brain barrier and starts stirring up many chemical reactions. The experts believe that due to the similarity in composition, Noopept works in a similar manner as the compounds belonging to the racetam family.
Due to this, we know that:
- It targets the acetylcholine system that improves the automatic nervous system and its response to stimulation from the motor neurons. This means your muscles will react faster than usual when triggered by an external stimulant e.g. a buzzing bee or a hot kettle.
- It increases brain energy levels. It does so by speeding up the blood sugar metabolism and oxygen levels in the brain. This results in higher brain activity and faster functioning.
- It enhances the NGF(Nerve Growth Factor) and BDNF (Brain Derived Nerve Growth Factor)
- It multiplies the number of synapses present in the central nervous system (CNS). The increase in number means greater neuron connectivity, which accelerates the speed of message transmission between the brain and neurons.
- Most importantly noopept attacks the glutamate receptor areas and slows down its breakdown.
Why is all this important?
Noopept is able to catalyze almost all the essential chemical reactions in the brain that keep it highly active. As a result, the user feels alert and ready to take in more information than he normally does.
Moreover, the inhibition of glutamate breakdown is the most crucial action that Noopept performs. This is because glutamate is a potent neurotransmitter that helps in most of the major cognitive functions. Therefore, the reduction of the chemical break down directly affects the cognitive functions (e.g. like thinking, clarity, memory retention, concentration, focus and the ability to decipher complex idea)
Researchers claim that this might be the best nootropic synthetically manufactured in the present times. This is because it is highly soluble and has a high rate of bioavailability. These terms mean that the body takes in and uses all the substance consumed, that too at a highly fast rate.
This makes Noopept a powerful drug that the body responses to within 15-20 minutes.
Noopept is the latest brain booster that has the ability to cover several aspects of brain activity. This is probably why it is considered one of the best nootropics out there.
However, you might have gotten bored learning about the mechanism and composition of the substance. You will probably be wondering when we’d answer the more practical questions that have popped up in your mind.
- How does Noopept work?
- Why should you be taking it?
- Does it help in restoring the brain power you have lost due to age?
Here is a list of benefits that might answer your questions:
- Improves Memory and Cognition
- Do you want to boost up your brain power?
- Then Noopept is your solution to getting smarter.
It primarily operates to enhance the cognitive activities of the brain. As a result, the user is able to learn and comprehend new facts and information at a better rate. Not only that the chemical also improves memory recall and retention that helps you solve problems, answer questions and just be less forgetful in everyday life.
1. Keeps the Brain Healthy
Do you know what a healthy brain needs?
It needs a consistent supply of oxygen and glucose to keep its energy level up. Noopept achieves this by speeding up the circulation of blood in the brain region. As a result, the mind remains active and productive for longer durations.
Not only does the drug prevent the brain from draining out, it also cleans the brain from toxins like lipids and potassium-based toxins that start accumulating during the extensive chemical activity.
How does it do that?
Noopept detoxifies the brain cells by working as an oxidizing agent that breaks down the toxins and clears the dreaded brain fog.
2. Improves Anxiety
Noopept just doesn’t help you become smarter it also makes you calmer. The drug releases a substance called cycloprolylglycine that helps soothe your frantically anxious mind. Lower anxiety levels can help regulate your emotional balance.
Therefore, nootropic may be able to keep you calm, happy and less prone to stay up at night.
3. Prevents Stress
Do you feel stressed out?
Noopept cures this by reducing the production of stress-inducing proteins. It probably does this when it is on its detoxification spree.
4. Improves Alzheimer’s and Parkinson’s
Noopept wasn’t always the ‘smart pill’ in town. In the past, doctors gave it to patients suffering from brain degeneration. It was specifically given to reduce symptoms of Alzheimer’s and Parkinson’s disease. This is because it improves memory storage and retention and also helps with the nerve growth and repair.
Other than that Noopept also:
- Enhances communication
- Protects and repairs the brain from damage
- Boosts the development of nerve and synapses
Do you want to maximize the benefits of Noopept?
Sure, you do. The smartest way to perk up your drug potential is through stacking. It basically involves the consumption of two separate supplements together. This nifty trick synergizes the effects and neutralizes their side effects.
The best Noopept stacks are the ones that pile up one or two nootropics drugs. The synergized energy of these stacked up supplements are able to create a power-packed brain boosting formula that works wonders.
Noopept and Choline Supplements
Noopept and choline is a match made in heaven. They combine their forces to boost up your memory. This is because both supplements are independently working to improve memory and cognitive functions.
How does this combo work?
Noopept makes the brain more responsive to the reaction of choline. Both then work towards enhancing the neurotransmission process in the brain. They do this by triggering the active secretion of neurotransmitters like acetylcholine and glutamate.
Next, there is an extensive variety of choline supplements present in the market. You can pick any of them, from choline bitartrate to citicoline, to create your stack.
Other popular Noopept stacks include:
- Noopept and a member of the racetam family
- Noopept and the Mind Pro Lab (a pre-formulated stack of nootropics)
While stacking, keep in mind to use a proper ratio of 3:1 to create your stack. Here the one will always depict Noopept.
Noopept is available in capsule and powdered forms across the market. Due to its potency, it is better to take the drug in small amounts.
How much noopept to take a day?
Experts advise first-timers to consume the supplement in a fairly low amount ranging from 6- 10 mg per day. They may gradually increase the dosage if the supplement is working for them and creating no dire side effects or allergic reactions.
How much noopept should You take?
The recommended dosage for an average user is 10-30 mg per day for up to fifty-six days.
Does age matter?
Yes, age does play a part in the proper consumption of this supplement.
Firstly, the dosage can increase with age. For example, an aged man suffering from memory loss will be required to consume a greater dose of the supplement than an average healthy man in his forties.
Apart from this, the supplements are off limits for women who are pregnant, breastfeeding and children under the age of sixteen. This is a safety precaution taken to protect the babies and children from the powerful influence of the drug.
The rise in popularity has made Noopept a much sought-after drug. This is why medical practitioners are pursuing extensive research on the safety and prevention of the smart pill.
Clinical trials prove that the supplement is safe to use when taken in small amounts. It is also said to be low in toxicity and does not induce addiction in the patients. Therefore, you can easily break out of the habit of taking the drug on a regular basis.
Other than that high doses of Noopept may lead to side effects:
- Irritability due to the hyperactive brain
- Fatigue after the effects decline
- Gastrointestinal issues
All experts emphasize that Noopept supplements are the most powerful form of nootropics accessible to you. It is your responsibility to use it and not abuse it!
If you have a vague idea about Noopept’s conception then you might have doubts about it being legal in the US. We assure you that the supplement’s Russian origins should not be your concern. The US government considers the drug safe and legal to use.
This is why it is easily available in the pharmacies and drugstores that sell nootropics. You can also buy it online without any problems.
What kind of supplement should you get?
Noopept supplement comes in three forms:
We suggest that you buy the powder form. This is because it helps the users to modify and monitor their dosage according to their needs. More importantly, the powder form is the purest form of the substance. This means it is highly-soluble and has the ability to cross the blood-brain barrier without limitations.
Is this drug really effective?
Facts show that it is. However, you really want to be sure of the results, right?
Fret not! We have got your concerns covered.
Here is what the users who have tried Noopept have to say:
A new user claims that,
‘’ I found Noopept to be effective. It made me calmer, more focused, and improved my memory skills.”
An engineering student recommends this drug by saying,
“So far I have seen no side effects of this drug. Therefore, I will keep using it until I feel the benefits. Noopept is an ‘all rounder’ cognitive enhancer that helps me remember facts and equations and I have a good test record to prove this.”
Other reviews tell about how the users felt that their mind operated on a higher level when they took this supplement on regular basis. They added that the supplement could lift their brain fog and make memories clearer than before.
In short, people from all walks of life are using this brain-booster to activate their memory skills.
What do you think?
Are you ready to try this smart drug?
- Cyclopropyl glycine and proline-containing preparation noopept evoke two types of membrane potential responses in synaptoneurosomes.
- Noopept efficiency in experimental Alzheimer disease (cognitive deficiency caused by beta-amyloid25-35 injection into Meynert basal nuclei of rats).
- Studies of long-term noopept and afobazol treatment in rats with learned helplessness neurosis.
- Novel nootropic dipeptide Noopept increases inhibitory synaptic transmission in CA1 pyramidal cells.
- Early postnatal effects of noopept and piracetam on declarative and procedural memory of adult male and female rats.
- Impairment of learning and memory after photothrombosis of the prefrontal cortex in rat brain: effects of Noopept.
- The nootropic and neuroprotective proline-containing dipeptide noopept restores spatial memory and increases immunoreactivity to amyloid in an Alzheimer’s disease model.
- Genotype-dependent characteristics of behavior in mice in cognitive tests. The effects of Noopept.
- Original nootropic drug noopept prevents memory deficit in rats with muscarinic and nicotinic receptor blockade.
- Noopept stimulates the expression of NGF and BDNF in rat hippocampus.
- Neuroprotective and nootropic drug noopept rescues α-synuclein amyloid cytotoxicity.
- [The original novel nootropic and neuroprotective agent noopept].
- [Comparative study of the long-term behavioral effects of noopept and piracetam in adult male rats and female rats in postnatal period].
- Effect of noopept and afobazole on the development of neurosis of learned helplessness in rats.
- [Genotype-dependent mice behavior in cognitive tasks. Effect of noopept].