Hordenine is a natural chemical found in a number of plants, like bitter orange and barley grass. It is a popular nootropic, which serves as a herbal MAO inhibitor. Thus, it helps enhance cognitive function like focus and concentration, promoting higher levels of energy, and improving overall mood by producing euphoric feelings.
People often stack Hordenine supplement with Phenylethylamine (PEA) to further enhance the cognitive functions.
An interesting function of this nootropic is that it can speed up the metabolism while suppressing the appetite at the same time. Hence, it works like a charm for athletes, bodybuilders, and people who simply want to shed some pounds and get fit.
Also known as N, N-dimethyltyramine, Hordenine is an alkaloid with adrenergic properties. It is responsible for the release of neurotransmitters adrenaline and noradrenaline. These neurotransmitters boost energy and improve focus. They are also involved in the flight or fight response.
Not only this, the forensic toxicology reports using this compound for measuring beer consumption, as Hordenine levels increase greatly in the blood following beer consumption.
With its vast range of modes of action, Hordenine offers several health benefits to its users.
You can enjoy the cognitive and physiological benefits of Hordenine by taking its supplement. However, note that since its effects are short-lived, you would have to take high dosages of this supplement to bring about any prominent effect
- It helps in weight loss.
- Helps in boosting your energy levels while improving focus and motivation.
- It is a natural MAO inhibitor that is great for enhancing mood.
As mentioned above, the mechanism of action of Hordenine involves working as an MAO inhibitor. Monoamine Oxidase (MAO) is an enzyme that is responsible for the breakdown of neurotransmitters, such as dopamine and phenylethylamine. These neurotransmitters are actually mood-regulating hormones. Hence, by inhibiting the action of MAO, It helps in increasing the levels of these hormones and thus produces positive feelings in the brain.
Typically, if you take a Phenylethylamine HCL supplement, it will surely give a boost to your mood but this boost will only be short-term because MAO will soon metabolize this chemical. Alternatively, if you combine Phenylethylamine with Hordenine, you can cause a hindrance in the metabolism process and produce positive feelings in the brain for longer periods of time.
In addition to this, It acts as a stimulant for the adrenergic system. It successfully passes the blood-brain barrier to enter in the central nervous system. It also blocks the removal of norepinephrine from the synaptic cleft and thus, helps in increasing its levels.
Moreover, It serves as a vasoconstrictor, meaning that it constricts the blood vessels and passageways. Not only this, it also acts as an anti-asthmatic and cardiotonic substance.
Yet another interesting mode of action of Hordenine is that it releases a number of fatty acids. Upon liberation and oxidation of these acids in the body, you will see changes in the body’s composition. Through this mechanism of action, Hordenine supplement plays a role in the realignment of the body’s set point. Since your body would want to maintain the state of equilibrium, it is clear why it will resist any changes in its mass.
Following are the five interesting benefits of Hordenine supplement.
1. Promotes weight loss
The primary and perhaps the most amazing benefit of this supplement is that it increases the energy levels and helps control appetite and lose fat at the same time.
This effect is not in any way restricted to athletes and bodybuilders – it may be more prominent in them though – but even if you are not very active physically, you may also experience it.
What can possibly be better than burning calories even while at rest? With the Hordenine supplement, now you have the option of an easy fat loss.
Additionally, It suppresses the appetite by slowing down the digestion of food. This way, it becomes easy to survive not eating anything in between the main meals. In turn, this reduces rather eliminates hunger pangs and unhealthy food cravings, decreases the overall calorie intake, and speeds up the satiation process during eating.
2. Increases alertness
Before an event of horseracing, Hordenine was injected into some horses. Within two minutes, there was an increase in their alertness level accompanied by a 100 percent increase in the heart and breathing rate. However, the effect was only short-lived and lasted for no more than 20 minutes – and oral intake of Hordenine did not increase alertness. The side effects observed included sweating and immediate defecation.
Another study conducted on rats found that Hordenine enhanced the response to noradrenaline by 65 percent. A guinea pigs study also revealed similar results.
On an interesting note, the Hordenine did not cause any direct changes in the body. This suggests that instead of directly increasing alertness, the supplement does so in an indirect manner by stopping the removal of norepinephrine.
3. Increases energy levels and improves focus
Apart from the weight loss benefits, this supplement is highly popular for the cognitive benefits that it offers. As experienced by the users, It causes mental energy to skyrocket. It provides a massive boost to the productivity levels. It can also increase the motivation levels, particularly sex drive.
The reason behind the increased energy levels and improved focus is that Hordenine increases the response to noradrenaline. Hence the positive noradrenaline effects!
4. Protects the skin
Overproduction of a skin pigment called melanin is responsible for the development of skin complications, such as freckles, melasma, and age spots.
While a variety of skin-tightening products that claim to decrease melanin are available, they can cause toxicity, giving way to skin cancer and other skin problems.
Therefore, It serves as an effective alternative option for skin products, as it decreases the production of melanin in human cells by 30 percent. It does this by inhibiting the production of cAMP, which produces the protein needed for creating melanin.
5. Enhances mood and protects the brain
By not letting MAO break down dopamine and phenylethylamine, It helps in producing mood-regulating effects. It promotes positive feelings and boosts overall mood.
Moreover, it helps in protecting the brain functions. Some cognitive benefits of Hordenine supplement include an increase in the duration of attention span, better focus, and concentration level to avoid distractions, and reduction of brain fog.
The safety profile of Hordenine supplement is very strong. Most healthy adults can easily tolerate it well.
Nevertheless, Hordenine being a stimulant may not be a good option for people struggling with heart conditions and high blood pressure.
In such cases, it is better to consult a doctor before taking the supplement – after all, it is better to be safe than sorry!
Also, you should never stack Hordenine with MAO inhibitors or prescription drugs for anxiety and depression.
When it comes to the side effects of Hordenine, taking the right dosage of the supplement is the key. Anything higher than the recommended dose can lead to potential side effects, such as dizziness, anxiety, nausea, rapid heartbeat, insomnia, mood swings, and upset stomach. However, these side effects only arise when you overdose on the supplement. Otherwise, it is perfectly safe for use. Upon experiencing any of these side effects, consider discontinuing the dose and seeking immediate help from a doctor.
How much hordenine to take per day?
The typical recommended Hordenine dosage is up to 30 mg twice or thrice a day.
Is hordenine good for bodybuilding?
If you are looking forward to building mass and enhancing your workouts, obviously you will require more intense bursts of energy. Thus, in this case, it would be best to take a dose about 45 minutes before your exercise routine.
When do you take hordenine?
On the other hand, if you want to use Hordenine for weight loss and fat burning, consider taking the first dose in the morning on an empty stomach and then the second one after about 6 hours. You would not want to take it late in the afternoon because the energy boost would probably disrupt your sleep at night.
When it comes to combining Hordenine supplement with others, it actually works really well with caffeine, PEA, and L-Carnitine for getting rid of fat and improving energy levels.
You can also stack it with some nootropics, such as Choline, Piracetam, and Aniracetam to experience enhanced cognitive effects and increased productivity.
There are a number of positive reviews of Hordenine. Even though some users were not sure about using the supplement in the first place, they were glad that they did anyway.
Many Hordenine users, including both athletes and non-athletes, reported experiencing fat loss and appetite suppressing benefits of the supplement.
Some reviewers mentioned that they experienced increased levels of energy throughout the day, both physical and mental. They observed that the supplement provided them with a serious stimulation and improved their overall well being in addition to inducing feelings of pleasure with no signs of addiction.
So, if you want to aid your weight loss efforts and make your fitness journey effortless with your body pumping with energy at all times, Hordenine supplement is the way to go!
Several studies have been conducted to confirm the safety status of Hordenine supplement. Under the light of these studies, healthy adults seem to tolerate it quite well and hence, it is safe for consumption. Research shows that this supplement works like a charm for the users and offers significant weight loss and energy boosting benefits at the cost of absolutely nothing! However, since this supplement falls under the category of mild stimulant, people who suffer from a heart condition or high blood pressure should not take it.
For a safe consumption of Hordenine supplement, you need to be careful about the dosage. Following the recommended dosage is the key to enjoying its benefits and avoiding the potential side effects.
In case a user takes a much higher dose than recommended, he/she may experience some mild side effects, such as insomnia, mood swings, anxiety, and rapid heart rate. If you experience any of these side effects, we strictly recommend you stop taking the supplement.
It would be better to discontinue the supplementation for a few days if this happens and if you would still like to continue taking Hordenine, we would suggest you talk to your doctor or a medical health professional to make sure that it is safe for you to continue the supplementation. Also, make sure you always stick to the recommended dosage.
However, as long as you do not go overboard with Hordenine supplementation and follow the recommended dosage guidelines strictly, it is 100% safe for consumption. It does not pose a risk for any serious side effect and is truly a dream weight loss supplement!
While you may find Hordenine in many fat-burners and pre-workout supplements, it is also available in single-ingredient form as Hordenine Hcl.
You can find these supplements at various online stores at very reasonable prices. Many online vendors sell Hordenine, both in powder and capsule form.Thanks to the advancement of technology in the modern world, all you have to do is find out a trusted online store that sells premium quality Hordenine supplement and place your order. Pay for it online or wait for a few days and pay cash when the deliveryman arrives with your order.
This is the easiest way to get your hands on this magical supplement while sitting at home, not to mention save your time and energy by not going to a physical pharmacy or a medical store. While Hordenine supplement aims to make your weight loss journey easy, the online vendors make it even easier!
- Screening and confirmation of drugs in urine: interference of hordenine with the immunoassays and thin layer chromatography methods.
- Biologically active secondary metabolites of barley. IV. Hordenine production by different barley lines.
- The action of hordenine on the superior cervical ganglion of the cat.
- Cactus alkaloids. VI. Identification of hordenine and N–methyltyramine in Ariocarpus fissuratus varieties fissuratus and lloydii.
- The distribution of tyramine, N-methyltyramine, hordenine, octopamine, and synephrine in higher plants.
- Certification of standard reference materials containing bitter orange.
- Mass spectrometric determination of the predominant adrenergic protoalkaloids in bitter orange (Citrus aurantium).
- Chromatographic and electrophoretic methods for the analysis of phenethylamine [corrected] alkaloids in Citrus aurantium.
- Rapid formation of N-nitrosodimethylamine from gramine, a naturally occurring precursor in barley malt.
- Revised NMR data for incartine: an alkaloid from Galanthus elwesii.
- Antimicrobial evaluation of clerodane diterpenes from Polyalthia longifolia var. pendula.
- Changes in apolar metabolites during in vitro organogenesis of Pancratium maritimum.
- Selective inhibitors of monoamine oxidase type B and the “cheese effect”.
- Action of various sympathomimetic amines on the isolated stripped vas deferens of the guinea-pig.