Galantamine Hydrobromide is a natural nootropic with an amazing potential to enhance memory function. When taken as a supplement, it can increase the rate of memory formation and improve the retention of facts and little details. People suffering from some forms of degenerative cognitive disorders may also benefit and improve their memory function from Galantamine supplement.
These supplements serve as a miracle worker when it comes to cognitive functioning. It not only enhances both short-term and long-term memory but also improves reasoning, mental processing, creativity, focus and concentration, and basic intelligence.
Before we move on to the benefits and mode of action of Galantamine supplement, let us discuss what this powerful supplement really is.
Galantamine is a plant alkaloid meaning that it occurs naturally. Nitrogen atoms mostly make up this basic compound that helps treat Alzheimer’s disease and other memory-related problems.
One can find this compound in the bulbs of some flowers – the Galanthus flowers, which include Caucasian Snowdrop, Red Spider Lily, and some daffodils.
Researchers originally discovered Galantamine in Russia and then studied it in the Soviet Union and Eastern Europe during the 1950s. This compound caught researchers’ attention because of the inhibition effects it shows against Acetylcholinesterase. The researchers soon found out and extracted its active ingredient. Finally, Dimitar Paskov developed the drug in 1959.
Since then, people throughout Europe have used this drug to treat various conditions, including myopathy, myasthenia, and sensory or motor dysfunctions. Galantamine is now an approved treatment option for Alzheimer’s disease according to the United States Food and Drug Administration (FDA).
- It helps in improving mental and memory functions.
- Constrains the production of acetylcholinesterase enzyme in the brain.
- It promotes brain cell health and boost your concetration.
There are various uses of Galantamine. This supplement is widely used to treat dementia – confusion ranging from mild to moderate severity – related to Alzheimer’s disease. Although it does not cure the disease, it significantly helps in performing and keeping up with daily functions by improving awareness and memory.
Moreover, people use this cognitive enhancer to boost their mental activity and relax. Also, they often take it as a lucid dream pill because it helps them fall asleep easier and faster after a long, stressful day. Galantamine tends to reduce the anxiety levels that accompany a high-stress day and make it challenging to fall asleep.
In addition to helping the users fall asleep easier, this supplement improves the quality of sleep, allowing them to enjoy a deeper level of sleep while their bodies recover and repair. Since memory formation occurs in the deepest stage of sleep – the REM cycle, Galantamine plays an effective role in improving memory.
- You must be wondering how Galantamine works in the body to yield such amazing benefits. Well, this supplement has two important mechanisms of action.
- The first mode of action of this supplement involves the inhibition of an enzyme called Acetylcholinesterase. This enzyme is involved in the destruction of used Acetylcholine molecules within the nerve synapses while the neurons form new synapses for the next nerve impulse. By decreasing the effect of this enzyme, Galantamine helps in increasing the level of Acetylcholine circulating within the brain.
- Galantamine also works by binding itself to the receptor sites of Acetylcholine, hence making them even more receptive to the neurotransmitter.
The bottom line is that Galantamine supplement works on both sides of the equation to promote Acetylcholine activity.
People with Alzheimer’s disease struggling with dementia have low levels of Acetylcholine in their brain. Hence, by preventing the destruction of Acetylcholine, Galantamine significantly reduces the symptoms of dementia.
Increased levels of Acetylcholine activity pave the way for a number of Galantamine benefits.
This supplement improves synaptic plasticity and makes the memory formation process better. Upon Galantamine supplementation, it becomes easier for your brain to adapt and respond to the stimuli in a better way. This magical supplement makes learning easy!
It also plays a key role in memory retention. You can increase the speed of memory recall by taking this supplement. Additionally, you may also experience improved focus and concentration level, enhanced decision-making skills, and an increased attention span.
Not only this, Galantamine supplement can positively affect your sleep too. To be better able to relax and enjoy a deep peaceful sleep, consider taking this supplement. With decreased levels of stress and anxiety, you will be able to fall asleep quicker and wake up feeling as fresh as a daisy! Galantamine is also popular for inducing lucid dreaming and/or out of body experiences. It actually increases the odds of lucid dreaming with a dosage of 4 mg to 8 mg after five hours and meditation.
While the FDA has approved to use this supplement for Alzheimer’s disease, evidence shows that it can also have positive effects on other conditions, such as ADHD, ADD, and other forms of dementia. Galantamine can also be beneficial for reducing some symptoms of stress and anxiety, autism, including lethargy, irritability, and social withdrawal.
Let us discuss the role of Galantamine in memory improvement in a bit detail.
This nootropic supplement is great for promoting memory function even in people with certain degenerative cognitive disorders. It also increases the rate of memory formation and promotes the retention of facts and details learned in both short-term and long-term.
Galantamine increases the levels of certain brain substances that improve memory function and clarity of thought. It is also known to interfere with an enzyme that is responsible for the breakdown of acetylcholine. Acetylcholine is an excitatory neurotransmitter that plays a key role in cognitive function. Decreased levels of acetylcholine seem to be the cause of various cognitive problems. Galantamine promotes the activity of this neurotransmitter and thus, helps with memory loss and Alzheimer’s disease.
Galantamine supplementation promotes cognitive function, brain activity, memory, concentration, memory recall, the speed of cognition, and vigilance.
Both healthy and brain-damaged adults seem to benefit from this supplement. They experience a significant improvement in their basic fluid intelligence, mental processing, reasoning, and creative thinking.
Considering these memory-related benefits of Galantamine, people use it as a supplement to treat vascular dementia, Alzheimer’s disease, and other conditions manifesting memory loss.
Galantamine is known for its powerful mind-inducing effects. It promotes vivid dreams and supports the state of lucidity, allowing the user to both control and better remember the dream experiences.
By increasing the levels of acetylcholine in the brain, this supplement lengthens the duration of REM sleep, promotes dreaming activity, and allows you to become self-aware in your dreams.
A lucid dream is when you are asleep but consciously aware of your dream state. This power enables you to control your dream experience and provides a chance for visualization practice or wish fulfillment.
A surge of acetylcholine activity causes you to enter the REM sleep cycle. This neurotransmitter plays a role in sensory perception, sustaining attention, and activating muscles and memory. High acetylcholine levels result in an increased duration of REM sleep. This neurotransmitter also promotes the synthesis of new experience through memory consolidation. This, in turn, promotes more detailed and vivid dreams and you end up remembering your dreams more clearly.
Furthermore, acetylcholine controls the working memory, which plays a major role in lucid dreaming. Thus, by increasing the levels of this neurotransmitter in the brain by taking Galantamine supplement, you can boost your dreaming activity and induce lucid dreaming. This is the reason why Galantamine is called the ‘lucid dreaming pill’. Since it is an acetylcholinesterase (AChE) inhibitor, it makes sure that enough acetylcholine is available to interact with the neural receptors.
When it comes to promoting lucid dreaming, Galantamine supplement tends to work great in combination with choline, a precursor to acetylcholine. By stacking these two supplements together, the stimulation of cholinergic neurons is increased from two directions at a time. Additionally, the Wake-Back-to-Bed strategy also proves helpful in inducing lucid dreaming. It involves sleeping deeply for 4 to 5 hours, waking up for a short period of time, and then going back to sleep.
Although the dose, frequency, and form of Galantamine supplement depend on your age, your condition and its severity, any other medical conditions that you might have, and your body’s reaction to the initial dose, here are a few basic recommendations on how to take Galantamine.
Given the power of this supplement, you do not have to take large dosages to experience its benefits. The general recommended dosage falls in between 4 mg to 12 mg taken twice a day. You should NOT take more than 24 mg in a 24-hour period.
Considering the long half-life of Galantamine, it is clear why you should not take too large a dose at a time. It tends to stay in the body for about 48 hours – and taking too much will only increase the chances of developing a resistance.
Moreover, you should always consult a doctor before taking this supplement.
If you want to take this supplement to treat dementia caused by Alzheimer’s disease, consider the following dosages and tips.
Adult Dosage (18 Years And Older)
- Starting dose: 8 mg daily in the morning
- Adjustment: After taking the starting dose for at least 4 weeks, your doctor might ask you to increase your dose by 8 mg every day.
- Maintenance dose: 16 mg to 24 mg daily in the morning
Oral Solution And Immediate-Release Tablets
- Starting dose: 4 mg twice a day, making a total of 8 mg per day
- Adjustment: Your doctor may increase your dosage by 8 mg every day after at least 4 weeks
- Maintenance dose: A daily dosage of 16 mg to 24 mg divided into two doses
Child Dosage (Below 18 Years)
Galantamine supplement is not suitable for use for children below 18 years of age, as there are no studies yet conducted.
It has several positive effects in the body.
A plant alkaloid that is a combination of two amino acids – tyrosine and phenylalanine, Galantamine is a selective Acetylcholinesterase inhibitor that stops the metabolism of the neurotransmitter Acetylcholine.
Acetylcholine is an essential neurotransmitter that plays an important role in the development of Alzheimer’s disease of mild to moderate severity due to its involvement in memory and learning.
Studies show that Alzheimer’s patients have lower levels of Acetylcholine in their brain due to its excessive metabolism. Upon Galantamine supplementation, they notice a significant positive change in their cognitive functioning.
In addition to this, Galantamine affects two neurotransmitters, adrenaline, and noradrenaline that regulate your energy levels and how your body responds to stress. Galantamine supplementation results in improved ability to handle stressful situations and a boost in the energy levels to perform daily tasks efficiently.
Although This supplement is very well tolerated and safe to use, it may cause some not-so-serious side effects.
Galantamine side effects that you can experience if you are one of the rare cases to see any include fatigue, headaches, nausea, dizziness, diarrhea, loss of appetite, and weight loss. They are of mild severity and go away on their own within a few days, hence do not pose any serious risk.
Majority of users who tried Galantamine supplement experienced positive results. Users struggling with Alzheimer’s disease noticed a great reduction in their symptoms of dementia. Patients who could not speak for more than a few seconds without forgetting what they wanted to say mid-way were able to talk about their entire day without facing any memory issue after Galantamine supplementation.
“Moreover, users who faced difficulties sleeping at night due to stress were able to fall asleep quickly and enjoy a deep sleep, feeling refreshed in the morning – all thanks to Galantamine!”
Whether you are seeking to improve your cognitive functioning or even your ability to deal with stress and anxiety, this brain supplement will work like a charm! Just make sure you talk to a medical professional and take sensible dosages to avoid any side effects and complications.
- Galantamine for Alzheimer’s disease and mild cognitive impairment.
- Long-term safety and cognitive effects of galantamine in the treatment of probable vascular dementia or Alzheimer’s disease with cerebrovascular disease.
- Galantamine in Alzheimer’s disease.
- Galantamine for Alzheimer’s disease.
- Clinical pharmacokinetics of galantamine.
- Galantamine–a novel cholinergic drug with a unique dual mode of action for the treatment of patients with Alzheimer’s disease.
- Long-term effect of galantamine on cognitive function in patients with Alzheimer’s disease versus a simulated disease trajectory: an observational study in the clinical setting
- The Prediction of Response to Galantamine Treatment in Patients with Mild to Moderate Alzheimer’s Disease
- Galantamine for Alzheimer’s disease.
- Galantamine: a review of its use in Alzheimer’s disease.
- Galantamine (By mouth)
- Galantamine for Alzheimer’s disease.