Centrophenoxine Review: How Safe And Effective Is This Product? – NOOTRIMENT

Centrophenoxine Review: How Safe And Effective Is This Product?

Introduction of Centrophenoxine (Better than DMAE)

Do you want to get a smarter, fresher, and more active brain? Do you want to prevent age-induced dementia and memory loss?

Then look no further, because we have a story to tell:

In 1959, medicine made a major breakthrough. A compound that could subdue the degeneration of the brain caused by age was discovered. Through extensive research, medical practitioners found out that this drug was helpful to both the senile and the young at heart. The compound assists in improving the cognitive functions, memory and learning process in the brain.

The drug is known as Centrophenoxine and it is one of the first few nootropics to be introduced. It is widely used by people to boost their brain power. It is also used to keep brain-related diseases like seizures, ADHD, dementia and Alzheimer’s disease at bay.

Centrophenoxine for Improve Memory Cell

Centrophenoxine for Improve Memory Cell

What is Centrophenoxine?

As stated above, Centrophenoxine is a drug that acts as a brain booster in the body; it does so by increasing the choline levels in the brain and inhibiting any form of brain damage that occurs due to age.

Centrophenoxine is an ester produced by the chemical combination of two essential chemicals:
  • DMAE (dimethylethanolamine): It is a form of ammonia that prevents the use of choline by peripheral tissues
  • pCPA(parachlophenoxyacetic acid): It is a type of auxin, a plant growth hormone that accelerates the development and growth of the living thing

Does Centrophenoxine Really Work?

Yes, it does work.

When we ingest the drug, it breaks down in the liver into two essential compounds, the amine DMAE, and the auxin pCPA. After that, both compounds get absorbed by the blood and enter the brain to stimulate its activity and hinder its degeneration.

Is Centrophenoxine Safe?

Centrophenoxine has been in use for more than fifty years. In that time, it has been proven to be safe for its users.

It is said to be a tolerable drug for most healthy adults and the senile suffering from memory loss. However, women that are pregnant/want to get pregnant or are breastfeeding are advised not to ingest the drug. Taking Centrophenoxine in those cases might cause complications in fetal development.

Others are recommended to take the regular dosage for Centrophenoxine, between 250-1500 mg per day.

Although the drug is safe, side effects due to overdosage or other reasons may cause:
  • Nausea
  • Dizziness
  • Stomach and intestine problems

How Does Centrophenoxine Boost Brain Power?

The best feature of Centrophenoxine is that it is water soluble. This makes the compound easier to ingest and also helps it travel freely throughout the body.

Although Choline and DMAE are naturally produced in the body, they are produced in minimal amounts. Those found in food have a low absorption rate. Hence, Centrophenoxine is a good alternative that counters the choline deficiency in the body and keeps the brain from malfunctioning.

Cholinergic Supplement
Brain Health Brain Health
Memory Memory
Neuro- plasticity Neuro- plasticity

How It Works:

  • It helps your memory and improves the acetylcholine levels in the brain.
  • Can inhibit the beta-amyloid residue and lipofuscin.
  • It helps you fight aging and boosts -brain health.
Between 250-1500 mg per day
Generally Well Tolerated

How does it do that?

Once the drug enters the body, it breaks down in the liver and helps to:

Activate the Neurotransmitters

Centrophenoxine for Cognitive Functions

Centrophenoxine for Cognitive Functions

Centrophenoxine is a source of choline; therefore it helps in the production of acetylcholine which is a neurotransmitter. This neurotransmitter allows the neuron signals to pass in the brain and it also increases the synaptic plasticity.

Due to the effects of acetylcholine, the brain becomes stimulated and performs its functions at a steady speed. This, in turn, helps boost memory retention, storage, learning skills and the brain-neuron communication that influences the nervous system.

Increase the Absorption Rate

Centrophenoxine’s solubility is the biggest reason why it is so effective, in comparison to the natural choline and DMAE dosages.  The latter two are difficult to absorb and have a slower speed than the Centrophenoxine.

Plus, the absorption rate also helps the brain to remain active. It takes in oxygen, glucose, and water at a consistent speed.

Therefore, the active brain keeps the drowsiness and lethargy away; it speeds up the thinking process and has more memory retention powers that help you remember things faster. Additionally, the active mind will also have enough energy to prevent the neurons and synapse from drying up. Otherwise, it will break the signals that transmit the messages in the brain, which is common in old age.

Moreover, the drug also cleans up the body from accumulating toxins. These toxins hinder the cerebral functions of the brain and increase brain damage.

Overall, Centrophenoxine is highly effective in keeping the wheels of the brain working without any problems.

4 Interesting Effects of Centrophenoxine and How It Is Produced?

The benefits of Centrophenoxine have been known in the medical world for half a century. Many clinical tests and researches have proven that the drug makes the brain more productive. It also prevents early symptoms of memory degeneration.

Four positive effects of Centrophenoxine in the body:

1. Anti-Aging and Detox Properties

Did you know that Centrophenoxine is also an anti-aging drug?

Age spots and liver spots on the skin are prominent indications of age. These spots start appearing because of high amounts of potassium accumulation under the skin(by Lipofuscin.)Accumulation in the vital organs of the body like liver, kidney, and adrenal glands also lead to these spots.

Centrophenoxine acts like a clean-up crew that clears the liver of these toxins and waste. It prevents accumulation and wiping out the stored toxins. As a result, your toxin level remains too low to create age marks on the skin.

2. Enhanced Memory

Centrophenoxine is a cholinergic drug, which means it contains a good amount of choline. It is a precursor to the production of the neurotransmitter acetylcholine.

Acetylcholine is the vital component of every neurological process. It helps in the communication between motor neurons and the brain. This helps the brain to function properly. It also helps to form new memories, store old ones and have a proper retrieval process.

3. As a Treatment for Dementia

Centrophenoxine was primarily made for dementia patients; this is why it is most useful in reducing the deterioration of the brain. The functions that lead up to senility and dementia are also reduced.

Because of the high absorption rate, Centrophenoxine makes it easier to break through the brain cell barrier that usually solidifies with age. Additionally, the drug keeps the intracellular water content and flow in check. It prevents dehydration in the brain that is generally one of the causes of dementia.

4. A Boost in the Brain’s Energy Levels

The engine of the brain is fuelled by oxygen and glucose; which is why low sugar levels or suffocation makes us dizzy and lightheaded.

Centrophenoxine not only increases the chemical reactions in the brain, but it also speeds up the absorption rate of glucose and oxygen. Hence, making sure that the ‘fuel’ is never drained out of the system, and the energy levels reach maximum potential.

Due to the high energy levels, the brain thinks and processes information quickly and effectively. Therefore, we call the drug a brain booster!

Centrophenoxine Core Brain Function

Centrophenoxine Core Brain Function

How Do I Maximize the Benefits of Centrophenoxine?

Centrophenoxine is a reliable and highly effective drug. Yet, many feel that it does not work on them or doesn’t meet up its potential. In such cases, one should start looking into the way one takes it. A proper dosage and Centrophenoxine stack for memory can boost the effects of the drug.

Proper Dosage

Do you know what happens if you neglect adequate dosage? You suffer from side effects like nausea, headaches, dizziness, and insomnia. This is why it is highly recommended that you use the drug in proper dosage and at appropriate times during the day.

So how much Centrophenoxine are you suppose to consume each day?

If you are new to it, then start out in small amounts; preferably 250 mg of powder or capsule at a time, twice a day. This will help you estimate the effects of the drug on your brain. While, regular Centrophenoxine users must take in 350-500 mg at a time, twice a day according to their needs.

Furthermore, you are requested not to take the drug at night. It disrupts your REM cycle and is likely to make you an insomniac due to the brain stimulation.


Do you know what stacking is?

Centrophenoxine Capsules

Centrophenoxine Capsules

It is the newest medicinal hack that is become very popular over the past decade or so.

Stacking basically involves taking two drugs together to maximize their benefits. This synergized version of the drug is better and more effective than the parts that make it up. You can reap in double the benefits by stacking Centrophenoxine with other nootropics. Stacking gives your brain the extra push to work to its full potential.

Moreover, stacking has been observed to eliminate the side effects of the two drugs that are being stacked up.

For example, Piracetam is another nootropic used to enhance the cognitive functioning of the brain. But it often results in headaches due to choline deficiency. However, when you stack it with Centrophenoxine (a source of choline) the drug will balance out the choline levels in the brain and nullify the side effects of the first drug.

This means you can use both drugs without fear of headaches. The other common stack partners include drugs from the Racetam family like Aniracetam and also Noopept.

Although stacking is completely safe to perform, you must be careful about the dosage. An improper dosage may reduce not only the effects of the drugs but also cause severe side-effects like heavy vomiting or mind-numbing nausea.

The common ratios in staking are 2:1 or 5:1, in which 1 denotes the Centrophenoxine. You must make sure that the overall dosage does not exceed 1000mg.

Side Effects of Centrophenoxine

Acetylcholine function in brain

Acetylcholine function in the brain

When taken with proper dosage, Centrophenoxine is probably one of the safest drugs out there in the pharmaceutical market. Unlike any other nootropic supplement, the toxicity levels of Centrophenoxine are almost equal to none.

However, it does contain DMAE (DiMethyl-AminoEthanol) which is also a safe compound but it can cause some mild side effects when consumed in excess.

DMAE is also a nootropic smart drug that is mostly used by people to enhance their cognitive senses. It also has little to no side effects if taken with proper dosage. There is the only minor difference between DMAE and Centrophenoxine, in fact, DMAE is actually a subset of Centrophenoxine. This means that Centrophenoxine inherits the chemical properties of DMAE and then effects in the almost similar way.

Taking an incredibly high dosage of Centrophenoxine will certainly cause mild side effects which include a headache, jaw clenching, dizziness, and nausea. If you go through any of these symptoms then you should immediately discontinue the drug and seek consultation.

However, there is nothing to worry about any serious implications after mistakenly taking the higher dosage of Centrophenoxine than prescribed. Pregnant women and those who are trying to get pregnant should avoid the usage of Centrophenoxine as it not safe for them.

Where Can I Buy Centrophenoxine?

Centrophenoxine is one of the most effective cholinergic drugs out there. It stimulates the acetylcholine and helps in boosting the cognitive and learning powers of the brain. This classic smart drug has always been in demand; this is why it is easily available worldwide.

However, Centrophenoxine is also known by other names. This is why you may find it hard to locate in your local pharmacy. The names Meclofenoxate and Lucidril are synonymous with the drug. If you find these available instead of Centrophenoxine then do not hesitate to buy them, they are all the same thing!

Is it available online?

The drug is legal, safe to use and does not require a doctor’s prescription. These factors make it easier to buy online.

In fact, we recommend that you purchase the drug online. Through a known and reliable vendor that delivers the medicine at your doorstep. This process will be stress-free, easy to manage and devoid of any long waiting queues.

What are you waiting for, old age or dementia?

Catch that memory train before it starts drifting off; stack up on those brain boosters right now.


  1. Effect of centrophenoxine against rotenone-induced oxidative stress in an animal model of Parkinson’s disease.
  2. Influence of prenatal applicated centrophenoxine on the postnatal increase in weight of the Wistar rats (author’s transl).
  3. Fluidizing effects of centrophenoxine in vitro on brain and liver membranes from different age groups of mice.
  4. Further evidence of centrophenoxine mediated protection in aluminium exposed rats by biochemical and light microscopy analysis.
  5. Effect of centrophenoxine on the antioxidative enzymes in various regions of the aging rat brain.
  6. The effect of centrophenoxine at the skeletal neuromuscular junction.
  7. Evidence for centrophenoxine as a protective drug in aluminium induced behavioral and biochemical alteration in rat brain.
  8. Potentiation of the cytotoxic action of melphalan and “activated” cyclophosphamide against cultured tumor cells by centrophenoxine.
  9. Lipofuscin in retinal pigment epithelium of rhesus monkey: lack of diminution with centrophenoxine treatment.
  10. Centrophenoxine-induced increase of beta-adrenoceptor density in brain cortex of old mice.
  11. Centrophenoxine improves chronic cerebral ischemia induced cognitive deficit and neuronal degeneration in rats.
  12. Comparative neurophysiological study of the nootropic drugs piracetam and centrophenoxine.,
  13. Comparative effects of centrophenoxine on the picrotoxin convulsive-seizure threshold in non-irradiated and irradiated mice.
  14. Age-related change in the multiple unit activity of the rat brain parietal cortex and the effect of centrophenoxine.
  15. Effects of centrophenoxine on body composition and some biochemical parameters of demented elderly people as revealed in a double-blind clinical trial.


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