Armodafinil: Health Benefits, Dosage and Where to Buy Online

Armodafinil: Incredible Benefits, Dosage & Where to Buy Online

A Brief Overview Of Armodafinil

If you have a hard time staying up during the daytime and that affects your work and performance, you should consider taking Armodafinil.

It is a prescribed oral drug that promotes wakefulness in the user by stimulating the brain. If you have a changed work shift and you are facing problem adjusting to the new work hours, feeling drowsy and sleepy, it can help you overcome it.

Armodafinil Cognitive Function

Armodafinil Improves Cognitive Function On The Brain

This supplement has a lot of benefits. It can assist in adjusting to a new time zone, overcoming changed sleeping and working hours, stimulating your performance under sleep-deprived conditions, and enhancing your brain functioning for mentally and physically challenging tasks.

How Armodafinil in the treatment of sleep/wake disorders

Armodafinil is a drug similar to Modafinil and is reported to increase cognitive abilities. Both the drugs are reported as functioning in the same manner, except that Armodafinil is stronger and has marginally different side effects and dosage level. It is a regulated prescribed drug and is medically used for the treatment of narcolepsy. The benefits of Armodafinil are associated with daytime sleepiness, high performance, and anti-fatigue effects.

It is an expensive drug as compared to other similar drugs like Modafinil and Adrafinil. However, it is stronger and safer than either of them, so that makes the price justified. Also, it produces better effects while still on a lower dose. There isn’t a lot of research to back up Armodafinil, but there are several clinical trials under process. They will help us understand the mechanism, benefits and side effects of this precise prescription drug.

This article presents a succinct overview of Armodafinil, outlining how the drug works in your body and what positive and negative effects it instigates on consumption.

What Is Armodafinil?

It is an oral drug from afinil drug family that serves as a wakefulness-promoting agent. It is in the crystalline powdered form in white or off-white color. It is found to be partially soluble in water, moderately soluble in acetone and readily soluble in methanol.

Armodafinil is also available in tablet form. You can acquire it in 50, 150, 200 or 250mg tablets. It is medically prescribed to patients to prevent excessive sleepiness that is caused by sleeping disorders like sleep apnea/hypopnea. Aside from treating the sleep disorder, Armodafinil is also found medically beneficial for conditions like depression and schizophrenia. This drugs that increase dopamine levels in the brain.

It is also available with the trade names Waklert and Nuvigel. Armodafinil is often deemed same as Modafinil which is a drug from the similar -afinil family and caters to the same medical condition of narcolepsy. This is not the case. Armodafinil cannot be substituted with Modafinil or considered it is bioequivalent.

The difference between the two is explained in the subsequent section ahead.

Armodafinil
Armodafinil
Eugeroic Drug
Energy Energy
Cognition Cognition
Motivation Motivation

How It Works:

  • It helps in keeping you awake for a longer period.
  • Helps in boosting the mental strength and performance.
  • It promotes focus and motivation.
Dosage:
Between 50 – 150 mg per day
Safety:
Generally Well Tolerated


How to Increase Dopamine Using Armodafinil

As discussed earlier, Armodafinil is a similar drug to the famous Modafinil. However, when it comes to increasing the dopamine then there is a huge difference in both of these drugs. Modafinil boosts wakefulness without stimulating the brain at all which means it doesn’t increase the level of dopamine. While on the hand Armodafinil stimulates the brain in order to induce wakefulness.

This stimulation of the brain releases large amounts of dopamine which relaxes the whole body in order to focus increase the focus. So, if you want to increase the dopamine rush in your body then all you have to do is swallow an Armodafinil.

How Does Armodafinil Work?

How to increase dopamine naturally using Armodafinil?

Drugs that improve your memory


Armodafinil Improves Memory

Due to a lack of research on this precise drug, the exact mechanism of Armodafinil remains unknown. It is reported to work similarly as Modafinil and other amphetamines. It promotes wakefulness in the user by stimulating their brains. Some of the research data indicate Armodafinil can influence the release of dopamine in the brain. Dopamine is a chemical neurotransmitter that is used by neurons in the brain to communicate with each other.

Racetam drugs generally comprise of two stereoisomers, R and S in equal proportions. These stereoisomers are usually responsible for instigating therapeutic effects in the user. Armodafinil, contrarily, only has one stereoisomer, R. This makes it functionally different from other racetam drugs like Modafinil.

Armodafinil, as per the limited scientific data available, is found to affect a variety of neurotransmitters in the brain and central nervous system. It is found to impact dopamine, serotonin, and orexin neurotransmitters among several others. It is presumed that Armodafinil works in a quite a similar fashion as Modafinil.

However, it does not bind the dopamine receptors directly and inhibits dopamine’ reuptake. This increases the circulation of dopamine in the neurons. Dopamine being a “feel good” brain chemical when gets affected by Armodafinil; it can help you treat how to relieve anxiety, depression and mood disorders.

Armodafinil’s effect on wakefulness and sleep pattern is mainly because of the influence it has on neurotransmitters orexin and histamine. Both these neurotransmitters are responsible for regulation of wakefulness, arousal, and appetite.

This eugeroic drug is also found to affect the areas of the brain that deal with conditions like depression and schizophrenia. As Armodafinil affects the neurons in the brain and increases the release of dopamine, it positively impacts not just depressive disorders like depression but also helps in reducing negative symptoms of schizophrenia.

Armodafinil Mechanism of Action

There is no precise definition of the action mechanism of Armodafinil. Its structural similarity with Modafinil suggests that it carries out its function in the same manner. The results inferred by the Armodafinil tests carried out on animals and in vitro studies state that this nootropic drug has wakefulness actions similar to sympathomimetic agents like amphetamine and methylphenidate.

The Modafinil-induced process of wakefulness is regulated by the α1-adrenergic receptor antagonist. Armodafinil as well as Modafinil work as indirect dopamine receptor agonists and get bind to the dopamine transporter. This ceases the dopamine reuptake, resulting in an increased flow of dopamine in the neurons, resulting in wake-promoting effects.

Are Nuvigil drug for Depression, Anxiety and Bipolar Treatment, Armodafinil, alongside wakefulness, instigates the psychoactive and euphoric effects in the users that cause an alteration in symptoms of stress and anxiety, mood, perception, and thinking and feeling process. However, like other euphoria-causing stimulants, Armodafinil does not impact the central nervous system or brain completely. It targets only specific areas in the brain and influences various neurotransmitters without causing any detrimental damage to the cognitive functioning and health of the user.

If you use Armodafinil orally with some additional fat, it gets absorbed more quickly and has more effectiveness. The peak level of Armodafinil in plasma is obtained after almost two hours of ingestion. The effect of the drug is quicker if it is taken with an empty stomach or in the state of fast. Though food has no impact on the functioning of Armodafinil, its efficiency is, however, impacted. It takes 2-4 hours for the drug to reach its peak level when taken with food.

Armodafinil for Narcolepsy Patient

Armodafinil Improves awakefulness for Narcolepsy patient

Armodafinil for Narcolepsy patient

Armodafinil is considered an effective treatment for excessive sleepiness, or narcolepsy. It was integrated into the treatment for sleepiness disorder in 2004 and is prescribed to the patients with obstructive sleep apnea/hypopnea syndrome and shift work sleep disorder.

The doctors prescribe armodafinil for its stronger effect than other eugeroic drugs like Modafinil and Adrafinil. This drug is effectual in improving wakefulness in the users and decreases daytime sleepiness by enhancing the functioning of the brain and reducing fatigue.

Narcoleptic patients are recommended to take Armodafinil once a day, preferably in the morning if they have daytime jobs. For night shift workers with work sleep disorder, the drug can be considered one hour prior to the beginning of the shift.

Cognitive Brain Booster

Armodafinil is a smart drug that has a tremendous ability to enhance brain functioning. Working as a brain booster, Armodafinil is widely used by students and people working in rather competitive fields. This cognitive enhancer helps you improve your brain’s performance and give it some additional boost to work with increased focus and concentration. Armodafinil helps in retaining memories and enhances your ability to recall things.

The mechanism of action is unknown, and there are no specific scientific justifications about how it works in the brain, but it certainly has some positive effects that can lead you towards the better quality of life. It reduces your impulsive actions and assists you in making the right decisions.

Armodafinil Vs. Modafinil

Armodafinil and Modafinil both are prescribed drugs and belong to the same drug family. They are reported to have almost similar effects. Being eugeroic stimulants, they help you deal with excessive sleepiness or narcolepsy. While they both are used to treat the same condition, their impact and reactions on individuals can vary substantially.

The difference between the two compounds lies in their chemical structure. Modafinil has two stereoisomers, R-Modafinil and S-Modafinil. Armodafinil, conversely, has only one stereoisomer, R-Modafinil. This denotes that Armodafinil is a variation of Modafinil and works slightly differently.

This Supplement is more effective than Modafinil and needs lesser dosage (150mg) to get same effects as the 200mg standard dosage of Modafinil. Both Modafinil cognitive enhancers showcase similar side effects like feeling edgy and headaches. However, in terms of mood enhancement, users report Modafinil to be better than Armodafinil.

3 Amazing Benefits of Armodafinil

Armodafinil shares benefit similar to that of Modafinil. This is primarily because of the structural similarity they share. Some of the benefits that Armodafinil has are discussed below.

1. Promotes Wakefulness

It was developed essentially for people who suffer from daytime fatigue. Serving as a wakefulness enhancer, it is beneficial for treating narcolepsy, sleep apnea, insomnia and drowsiness-like effects experienced during shift work.

2. Boosts Energy Level

This Supplement is gaining popularity among people because of its ability to boost energy levels without causing any adverse reactions. It is a prescription diet pill that provides effects similar to that of stimulant drugs but is sans any adverse consequence that can cause health problems.

3. Improves Alertness and Productivity

It is reported to have a long-lasting effect and is stronger than Modafinil or other eugeroic compounds. Using this precise drug, you will be able to experience clarity of mind that can help you focus better and stay more alert. It also enhances the brain functioning, escalating your overall productivity without causing uncomfortable sensations in the body.

Armodafinil Common Side Effects

The side effects are similar to that of other nootropic supplements. You are likely to face only mild adverse reactions after consuming Armodafinil. The side effects may range from nausea and stomach disorders to headaches, anxiety, and dizziness.

The potential side effects that are slightly more severe include allergic reactions that may cause itchiness or form blisters on your skin that may result into bleeding. If you experience any swelling around your face, mouth or any symptoms of an allergic reaction appear on your skin, stop using the drug immediately and consult your doctor.

Is Armodafinil Legal?

Armodafinil is an FDA approved a drug. It is legal to buy and use if you have its proper prescription given to you by your physician. In the United Kingdom, Armodafinil is placed in the category of “prescription-only medicines.” This necessitates the presentation of medical approval to purchase and use the drug. You are allowed to import a 3-month supply of Armodafinil on prescription.

This flexibility is not offered in Canada where you cannot import prescription drugs through mail or courier.

Armodafinil is regulated in all the countries where Modafinil is legal. So if you live in such a country, you can get your supply of Armodafinil by showing your physician’s prescription.

As for countries like India and Mexico, Armodafinil is not lawfully regulated there. It can be purchased and used easily through online vendors or nearby pharmacists. You do not require a medical prescription to get this precise drug.

Alternative Method to Buy Armodafinil without Prescription

Since Armodafinil is used for purposes aside from medical treatment for narcolepsy, it is high in demand. People tend to explore ways that do not require a prescription to buy Armodafinil. Several online vendors from the India and Mexico, where Armodafinil is not regulated, are illegally selling the drug without a prescription.

Considering its many benefits, if you want to order this drug, you can get your supply through an online pharmacy that stocks it. However, it is essential to check the authenticity of the vendor to ensure you do not incur any quality control problems later.

References

  1. Enantioselective HPLC resolution of synthetic intermediates of armodafinil and related substances.
  2. Armodafinil: a new treatment for excessive sleepiness.
  3. Armodafinil, the R-enantiomer of modafinil: wake-promoting effects and pharmacokinetic profile in the rat.
  4. Interaction profile of armodafinil with medications metabolized by cytochrome P450 enzymes 1A2, 3A4 and 2C19 in healthy subjects.
  5. Pharmacodynamic effects on alertness of single doses of armodafinil in healthy subjects during a nocturnal period of acute sleep loss.
  6. The efficacy and safety of armodafinil as treatment for adults with excessive sleepiness associated with narcolepsy.
  7. Effects of armodafinil in the treatment of residual excessive sleepiness associated with obstructive sleep apnea/hypopnea syndrome: a 12-week, multicenter, double-blind, randomized, placebo-controlled study in nCPAP-adherent adults.
  8. Armodafinil for excessive daytime sleepiness.
  9. Armodafinil and modafinil have substantially different pharmacokinetic profiles despite having the same terminal half-lives: analysis of data from three randomized, single-dose, pharmacokinetic studies.
  10. Pharmacokinetic profile of armodafinil in healthy subjects: pooled analysis of data from three randomized studies.
  11. Armodafinil in the treatment of sleep/wake disorders.
  12. Ready for takeoff? A critical review of armodafinil and modafinil for the treatment of sleepiness associated with jet lag.
  13. Armodafinil for treatment of excessive sleepiness associated with shift work disorder: a randomized controlled study.
  14. A double-blind, placebo-controlled study of armodafinil for excessive sleepiness in patients with treated obstructive sleep apnea and comorbid depression.
  15. Modafinil and armodafinil treatment for fatigue for HIV-positive patients with and without chronic hepatitis C.

Rate This Article
1 Star2 Stars3 Stars4 Stars5 Stars (No Ratings Yet)
Loading...

Leave a Reply

Your email address will not be published.